Morphine and codeine in oral fluid after controlled poppy seed administration
نویسندگان
چکیده
منابع مشابه
Determination of Morphine and Codeine in Serum after Poppy Seed Consumption Using Gas Chromatography – Mass Spectrometry
An analytical method is presented here for the assessment of morphine and codeine concentrations in human serum by employing mass spectrometry in the selective ion monitoring mode following its separation with gas chromatography. Deuterated (marked with heavy water) analogies of the analytes were used as surrogate internal standards. Samples were cleaned up using solid phase extraction. The tar...
متن کاملConcentrations of Morphine and Codeine in Paired Oral Fluid and Urine Specimens Following Ingestion of a Poppy Seed Roll and Raw Poppy Seeds
Interpretation of opiate drug test results can be challenging due to casual dietary consumption of poppy seeds, which may contain variable opiate content. Opiate concentrations in paired oral fluid (OF), collected with the Oral-Eze(®) Oral Fluid Collection System, and urine were analyzed after ingestion of poppy seeds from the same source, consumed raw or contained in a roll. In Part 1, 12 indi...
متن کاملOpioid disposition in human sweat after controlled oral codeine administration.
BACKGROUND Characterization of opioid excretion in sweat is important for accurate interpretation of sweat tests in drug treatment, criminal justice, and workplace drug testing programs. METHODS Participants (n=20) received placebo, 3 low (60 mg/70 kg) or 3 high (120 mg/70 kg) codeine sulfate doses (used as a model for opioid excretion) within 1 week. Codeine and metabolites in sweat were col...
متن کاملPlasma and oral fluid pharmacokinetics and pharmacodynamics after oral codeine administration.
BACKGROUND The ease, noninvasiveness, and safety of oral fluid collection have increased the use of this alternative matrix for drugs-of-abuse testing; however, few controlled drug administration data are available to aid in the interpretation of oral fluid results. METHODS Single oral codeine doses (60 and 120 mg/70 kg) were administered to 19 volunteers. Oral fluid and plasma were analyzed ...
متن کاملUrinary concentrations of morphine and codeine after consumption of poppy seeds.
A quantitative analysis of morphine and codeine in human urine was performed after oral intake of cakes containing commercially available poppy seeds in order to estimate the possibility of positive doping results. Therefore, eight products from different manufacturers (poppy seeds or baking mixtures) and origin were obtained and analyzed by gas chromatography-mass spectrometry for the presence...
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ژورنال
عنوان ژورنال: Drug Testing and Analysis
سال: 2014
ISSN: 1942-7603
DOI: 10.1002/dta.1742